Not a huge one, but it was nicer to have my most frequent points of interaction at the top. I deal with the code itself in my local repo. I don't need to know how many commits/branches/tags/contributors there are -- that is the redundant info for me, and that should have been shoved to the side.
If I'm using github's UI, it's because I'm managing a project. Might be nice to have a separate "management" interface you can opt into?
tldr: They moved all the "extra" stuff to the side, while keeping the info directly related to the git repo in the center. But the whole point of using github is the value they add, not the core functionality that I can already get through my commandline!