Twitter started with Rails, and at some point decided it was more efficient to do an incremental rewrite on the JVM.
I can rewrite the entire backend in a weekend in Python.
I'd bet it took Twitter a bit longer to replace their infrastructure, and they survived just fine.Build in whatever is rapid, for you. At this very moment. Using your resources.
Keep things service-oriented, decoupled. It'll be easy to replace things one component at a time, if needed.
in summary..
I think it's a perfectly cromulent platform to build on in terms of speed and scalability. But, in case you and I are wrong, follow my advice about staying decoupled and it won't hurt as much.