It's not as good as Python yet but rapidly getting better.

There's an excellent SQL abstraction library (Korma), Ring makes for a nice WSGI equivalent, Compojure and Clabango combined give you a Flask'ish experience, and there are a goodly number of Forms and validation libraries.

Some like to use CLJS on the frontend. There are libraries out there for making that nice.

I usually use vanilla jQuery or Angular on the frontend, no CLJS.

You need get more specific with your queries, I'm not going to write a novel at the merest hint.