Sure. I have a MacBook Pro for personal use, and at work I'm a Java developer using an iMac with a Magic Trackpad.
I don't use all the gestures, just a few of them. But I've been doing it for so long they're second nature to me.
Two finger scroll one of the most important. I remember trying to use friend's PCs before it became common and being frustrated every time.
Two finger click works like a right-click, so I don't need to hold a key or dedicate part of my touchpad to right-clicking.
Three finger swipe left/right is amazing. It functions as a forward/backward gesture. In Safari it moves through history. In IntelliJ (my IDE of choice) it does the same thing, which is invaluable. I don't even know the keyboard shortcut in IntelliJ, it just works. And it works in Chrome. And Xcode. Having a universal gesture is fantastic.
Another favorite is four fingers up, which activates Expose. When you're moving between multiple applications and copying & pasting it makes makes things so much easier. I don't have to move my hand off command-C/V.
Four finger spread shows the desktop, which I use occasionally.
Double-tap with two fingers zooms in iOS style in Safari, which can e useful
Double-tap with three fingers opens the dictionary (& Wikipedia!) anywhere in the os on whatever you tap on. Reading an article and don't know what something is? Just double-tap three fingers and a little pop-up tells you. It's one of those functions that's always been there but it's so easy to get to I actually use it now.
That's what I use. There are a few more. Four fingers together opens Launcher. In Safari the zoom out gesture (pinch two fingers) brings up a tab-list, but I keep forgetting that's there since it's a relatively recent add. Four fingers down is Expose for one application, but I don't have much need for that. Two fingers from the right edge opens the notifications in Mountain Lion (which I don't really use).
If you're a multi-desktop person, four fingers left or right switches between desktops (including Dashboard) and every full screen application. This also works for app switching on iPad 2/3/4s.
Really it's like using command-c/v to copy and paste or command-tab to switch applications. It's quick and easy to do, and you quickly forget it's there and start doing it automatically.
Honestly I hate helping coworkers with a problem in IntellJ because they all use normal mice and I can't easily jump back to the last place I did an edit (even in another file). I'm working on helping them and then all of a sudden there is a brain stall while I realize that I can't just do a swipe and have to think to go click on the tab I want.
I feel handicapped without them; like something is missing. I remember how much I liked getting a button on the side of my MS IntelliMouse I could use to go back when surfing, this is like 100x that.
Edit: It just occurred to me that these aren't default gestures. A few of them changed in Mountain Lion and I set my Macs back to the way Lion had them, so you may have to experiment.