On the other hand for the life science and research library community, friendfeed has become the de facto watercooler, especially for the computationally inclined. Even to the extent of conference reviews being presented in a journal like PLoS Computational Biology

http://www.ploscompbiol.org/article/info:doi%2F10.1371%2Fjou...

http://friendfeed.com/rooms/the-life-scientists

It provides a forum for discussion around things we do on the web and I can't think of another resource where doing it is as easy. Note that these are people who aren't looking to get a startup noticed, nor are they looking for page views, and many are not on Twitter. It's just an ideal medium for them.