This goes to the core of creativity: Creativity usually comes from combining things or ideas that are normally compartmentalized in others' minds. Have you ever noticed how most of the startup founders you know have a wide diversity of experiences to draw upon? Most of them have lived in foreign countries and are well acquainted with subcultures most of us are barely even aware of. The reason curiosity is such a positive trait is because it gives you more inputs to operate off of. The article gives a perfect example:
"A long time ago, when I was a columnist at the Las Vegas CityLife, my editor called me up one day and asked if me if I ever wanted to find out what was in the storm drains under the city. And because I have notoriously poor self-preservation skills, I grabbed a Mag-Lite and headed on down." That's the kind of crazy, insatiable curiosity that ends in you seeing the world differently. That's why innovators seem so crazy, but what they're doing makes complete sense in their minds.
In other words, in my mind it's impossible to draw a line between "innovation" and "iteration," because every innovation is really an iteration of different ideas no one had ever really put together before.