It's like saying that images are no problem for accessibility on the Web, because designers know to use alt text. Of course they know they should, but we all know what the reality is. A backup "portable" version of an app is like alt text in this way. Some developers would do the right thing; many won't, and the Web will be de facto locked in to x86 and ARM forever.
Won't developers have access to PNaCL runtimes? How is this so different than Apple developers having access to the other target hardware
It comes down to toolchains and the workflow they're optimized for. With PNaCL, the portable version is the primary target of the toolchain, from which one generates other native binaries. You can still generate native binaries separately, but ideally, PNaCL would lead.
If the tools lead naturally in the right direction, then developers do follow. If you're feeling really worried about it, define a distribution format that mandates a PNaCL entry.