In high tech this can get really messy, these are frequently inherently more fragile companies. My favorite example is from Robert X. Cringley in this great book: http://www.amazon.com/Accidental-Empires-Silicon-Millions-Co... ; from memory:
One day Intel's yields suddenly went to hell (that's the ratio of working die on a wafer to non-working, and is a key to profitability). And no matter how hard they tried, they could only narrow it down to the wafers being contaminated, but the wafer supplier swore up and down they were shipping good stuff, and they were. So eventually they tasked a guy to follow packages from the supplier all the way to the fab lines, and he found the problem in Intel's receiving department. Where a clerk was breaking open the sealed packages and counting out the wafers on his desk to make damned sure Intel was getting its money worth....
His point is that you can have a Fortune 500 company, normally thought to be stable companies that won't go "poof" without ample warning, in which there are many more people than in previous kinds of companies who can very quickly kill it dead.