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Horrbily one-sided. Wikipedia's article has both ways coffee is good and is bad for you.

http://en.wikipedia.org/wiki/Health_effects_of_coffee

The important thing is that the dosage makes the the medicine of poison, and that while drinking two or three cups a day may be better for your health than not drinking coffee, drinking ten cups a day is bad for you.

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Ignoring the specific number of cups for a moment, I like your discussion of dosage making something medicine or poison.

In medicine we say that drugs have a "therapeutic index". That is, there is some window in which the medication is more helpful than harmful. On the low side, there is just no effect. On the high side, toxicities dominate.

Makes me wonder if there's anything with the opposite progression:

No effect -> harmful -> helpful

I'd guess not, but I'm curious as to why.

Overload /limitations to adaptation.

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