Yeah, definitely! Here are the two I used - fair warning, one is a Nettuts article. It's not the best tutorial ever but I had never written any Python before reading it and I was able to pull out the useful bits and apply them to my own plugin.
http://net.tutsplus.com/tutorials/python-tutorials/how-to-cr... - If nothing else, this will at least teach you how a Sublime plugin works (like where it lives and how you add it to the editor and such)
After that, the Sublime API will take it from there - http://www.sublimetext.com/docs/2/api_reference.html
I took bits about how ST2 plugins are structured from the first article, then looked for 'how to do X n Sublime' in the second and once I got those down it was just a matter of Googling for "how to do Y in Python".
The basic gist of it is that a plugin for Sublime is just a Python script that lives in Sublime's packages directory (~/Library/Application Support/Sublime Text 2/Packages on a Mac). Create a folder named after your plugin, drop the python script in there, and then use Python + the Sublime API methods to interact with the browser.