and the problem with CPython is that is wouldn't be compatible with any of the office api's that are likely based on .net technology. so which one do you think would be better for office. I haven't done ms office automation since office 2k7 but that is the way it was heading.
edit: oh I see what you are getting at. a new product from a new company created at mit in 2012. https://www.datanitro.com/
I would argue that a $500 license is also not targeted at newbie programmers either.
can you run native python from excel without shelling out $500 ?