I'm mostly going to use this for parsing XML into some other formats and getting it into SQLite databases I think. The reason I would like to use Drake over 'raw' Python scripts is because it supports a lot of the mundane stuff that goes around the actual processing of the data, and I want to automate the processes.
I typically deal with sub-100MB XML documents, so processing them takes very little time, but having the quick iteration of changing the format and re-outputting is a key part of the development cycle for me, and I think very useful when you are experimenting with new data and seeing how it could be used. Doing quick transforms is awesome.