Well, the subscription box model is working out okay for the likes of Tonx (coffee - http://tonx.org - and delicious coffee at that) but I'm not aware that they're trying to go the Silicon Valley venture-capital startup route at all.
http://www.reddit.com/r/coffee: 35,566 subscribers http://www.reddit.com/r/Wicked_edge: 26,612 subscribers
I have a few real preferences, so "box o crap" wouldn't work as well for me.