If we ask this a different way, is there a single self executable file when written to the sector of the disk the hardware looks for can contain the instructions for the hardware and the weights all in one?
I can't thing of any informational theory reason why this can't be the case. The only thing I can think of structuring such far more complex and less worthwhile than just having separate layers. Dealing with this biological/intelligence mess in humans is already hard enough as it is.