I'm using NixOS "latest" on my workstation, for no particularly good reason.
One success I had was with building up a custom vim setup. I had previously been using Lunar and Astro as an opionated vim distro with LSP+Treesitter and some other "table stakes" things a modern editor should have. But there wasn't a clear way to install Astro in NixOS when I tried it manually. So I just told Claude Code what plugins and settings I wanted in neovim, and now I have a single file that fully describes my vim setup. Before with Astro and Lunar the configs were spread out all over a bunch of files.
I was also able to get Claude Code to bundle up gitbutler-cli, which I wanted to try but so far have not. It builds it from source because there was no existing derivation. It takes a stunningly long time to build, but otherwise it has worked very well in my simple testing of it. Plus, I can build on my powerful laptop and then use that to seed my old, slow ThinkPad T470s and even slower chromebook that I also put my config on.