In fact, I would say there's probably a very narrow set of circumstances where his back to the drawing board approach can be deployed successfuly.
That said, the 787 Dreamliner remains statistically one of the safest widebody long-haul aircraft in commercial aviation history, which I think is a Counterpoint. It achieves this despite any more globally diverse supply chain, and moving production out of unionized Boeing manufacturing plants.
Safety by Design and design for manufacturability can help eliminate the possibility of quality issues during production.