More of a generic engineering quip - if a gadget can't meet a spec, then either it wasn't designed to that spec, or it degraded after it passed QC.
I'm vaguely aware of the endurance running hypothesis. But a quick Google suggests that most humans had decent stone-age atlatls, bows & arrows, snares, and spears by ~50k years ago. That's >2k generations of selection where endurance running is not the highest-value skill for catching dinner.
> ... lactase persistence is a rare outlier of rapid adaptations within that time frame ...
Look at parts of the immune system which are needed to fight high-mortality diseases. The classic is https://en.wikipedia.org/wiki/Sickle_cell_disease#Genetics
> On a side-note ...
Humans have been concocting excuses to proclaim their own ancestry and blood "superior" for well over 7 millennia - https://en.wikipedia.org/wiki/Pharaoh#Divinity. Ditto ways to rationalize ruling class control over reproduction (and everything else) in the "lower" social classes. My own interest is more on esoterics, such as this unfortunate mutation - https://en.wikipedia.org/wiki/Vitamin_C#Synthesis - and things humanity may desperately need soon, like another 10 °C of heat tolerance.
(FWIW, my immediate association with Born to Run is musical - https://en.wikipedia.org/wiki/Born_to_Run )