Yes, 100%. I played around with building this last year and even a simple version was already fairly effective: https://notes.npilk.com/experiments-with-ai-adblock
One interesting thing is that it also removed some "internal CTAs" to engage (like "Start your day with our podcast!"). These aren't technically ads, so something like uBlock doesn't remove them. But honestly, I don't really mind having those filtered out too.