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Comment by Balooga | Hacker News Reader

This research already exists though. Obesity and being overweight increases the risk of sleep apnea, strokes, heart disease, diabetes, mental health problems, etc. etc

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Causality is an issue there, I would suggest that genetic auto immune issues that are rather wide spread can cause all of the above. I think people are finding that GLP-1s help with auto immune issues.

I can speak only for myself. But when I was overweight, the heels of my feet would crack into such deep fissures that I could remove skin like thick pieces of jerky.

I lost 90 pounds and now the heels of my feet are as soft and supple as a baby's bottom.

Being overweight causes all sorts of weird side effects.

The incidence rate of genetic issues generally doesn't change much over time due to how slow genes changes, so an increase in obesity rates from 5% to over 40% in just a few generations suggest the cause is very unlikely to be due to genetics.

In the US, I'm convinced that it was the food pyramid.

As a kid in the 80s, I wondered how it made sense that my diabetic father was told to follow the same model as non-diabetics, which emphasized carbohydrates.

"Revealed: group shaping US nutrition receives millions from big food industry" -- The Guardian[1]

[1] - https://www.theguardian.com/science/2022/dec/09/academy-nutr...

Not exclusively genetic but inclusively genetic. There are of course other factors involved and I think genes are a big one.

Nah you don't get to 40% obesity in some countries due to genetic issues.

It's all hyperpalatable foods and the effects of extra adipose tissue are know to be bad for pretty much every health metric under the sun.

Anectata: I sleep much better after losing about 25 kg, and don't snore anymore. I didn't really think before about how your airways can get fat, but now that they're thinner, I had to relearn how to swallow, because food/drinks tried to go up my nose. I guess my point is that resting better has all sorts of secondary improvements.

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