I get wrist pain as soon as I use anything taller than Apple’s flat Magic Keyboard and touchpad. I’ve used this combo for like a decade now and never experience fatigue. Once, I bought a fancy mechanical keyboard and I returned it within a few weeks as it immediately caused me wrist pain.
You can scoff at low travel and membranes all you want, but less movement = less fatigue, so I think they’re amazing.
Never thought about the climbing angle, but I’ll chime in and say that after I started climbing I’ve definitely not experienced more fatigue.