[1] https://bsi-inc.com/sds_pdf/sds_un_cure.pdf
As a chemist it’s a highly polar, very high boiling point solvent that is the “go to” when you can’t find a solvent your reactants dissolve in.
Acetone is less polar, more chemically reactive and lower boiling point. It’s rarely used as a reaction solvent due to its reactivity, but it is common in crystallizations.
Both are quite non-toxic (your body makes small amounts of acetone!), but I recall a cancer risk with high exposures of DMF (the example was tannery workers who sprayed it without any safety gear and got soaked).
Acetone only dries out the top skin layers, which immediately triggers a healing response and accelerates the shed cycle. Dermatologists use acetone prior to skin surgery to speed up the recovery.
It’s extremely safe. Your body naturally creates it and you exhale and piss it out every day. If you are having any long term health issues from exposure then this may indicate that your immune system is seriously compromised.