Anecdotally, multiple folks have said to me they don't drink coffee because it makes them anxious. Enough for me to take notice.
> In fact, none of the sleep researchers or experts on circadian rhythms I interviewed for this story use caffeine.
https://www.theguardian.com/food/2021/jul/06/caffeine-coffee...
Although, it doesn't make me feel anxious on most days, it's really only if I already have a prior reason, it just exacerbates it.
>In CD participants, indoles such as indole-3-propionic acid (IPA) and indole-3-carboxyaldehyde (ICA) and the neurotransmitter γ-aminobutyric acid (GABA) were significantly decreased.
GABA is an anti-anxiety neurotransmitter, it's what benzodiazepines mimic.