I disagree. I tried this once. Now you need a client access layer to touch the DB in any context. All your console tools no longer work well or at all. If they show up in URLs you need to deoptimize them for transport.
You give up a lot of convenience for this optimization. You should be absolutely sure your design requires it before using it.
Eg I save a date 18 months in the future in US Western time at 0600. 3 months from now the US gets rid of Daylight Savings. You saved it as 1400 UTC (which was correct), which is now an hour off because the local time zone is different.
Encoding it in local time fixes that, because it delays the TZ conversion until you need it and your times stay correct as long as you update tzdb like once a month.
Why would you store it as as str column and not the inbuilt type for this?
https://www.postgresql.org/docs/current/datatype-uuid.html
If you are using SQLite well I guess that doesn't work.