Usual espresso from 42mm puck is 18g of coffee beans in, something around 40g of total coffee out. This has 90…150 mg of caffeine. The study focused on people having more than 300 mg daily.

So don’t drink more than 2 cups per day and you’ll be fine.

The potential for there to be a mechanism that accelerates progression is a great thing to publish, but the data looks like it is in the "do you want to enjoy coffee for 5 years or go without to maybe avoid speeding it up a little bit" category.