Netflix uses AV1: https://netflixtechblog.com/av1-now-powering-30-of-netflix-s...
YouTube uses AV1. It's tough to be more mainstream than that.
Right click on a YouTube video and select Stats for Nerds. If your system is capable of it, chances are it will be playing back in AV1.
Most of the YouTube videos I watch these days are AV1 encodes. Sometimes it's in VP9 and occasionally it's H.264.