I know, it is a saying, but take a look at "important people" that lived 2,000 years ago. How many do you know? 5? 10? What about the other millions of people?
Thing is, this whole "dent in the universe" thing leads to discussions that are pretty close to comparing cock lengths. "My goal is so much more worthy than yours - I'm making a dent in the universe", which I find highly hypocritical.
I believe there's no fundamental difference between the "dent-in-the-universe-webservice" that some people claim to develop and, say, lolcats. At least the latter made millions of people laugh for a moment.