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QoR for advanced and large designs can change wildly between versions (for better or worse.)

Read the article. The old version will not be supported soon. I assume that means you also won't be able to register it.

People are still using Vivado 2019 (and earlier) and ISE. The ability to use these versions isn't going anywhere.

Yes, working with recent distros. At some point I spun up a vm because there was no way to make it work after an upgrade.