You bet against skilled people who set the stakes, so, yes, by observing numbers you can win in Keno, but if you comply to the TOS you will not win big money. The only chance to be able to "game the system" is to bet on something that lotteries brokers does not have time to look at, like 3rd Bulgarian bocce league matches.
The problem is that you need to somehow become an expert in 3rd Bulgarian bocce league and the money which are there are generally small.
I was investigating this (again) when AI showed up, as in theory it makes easier some analysis, but the big guys are also using AI.