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Something I'm surprised this article didn't mention is that sometimes the anti-inflammatory is the point. If you have swelling along with the pain then ibuprofen or any other NSAID is going to be much more effective. That would be the main reason to go with ibuprofen in my opinion. But again if you take medical advice from an internet comment you're already doing it wrong.

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> if I needed a painkiller, I’d try to take ibuprofen rather than acetaminophen. My logic was that if eight grams of acetaminophen could kill my liver, then one gram was probably still hard on it.

This article is explicitly considering usage as painkiller.

You can’t use Tylenol as an anti-inflammatory so it’s meaningless to compare them for that distinction usage.

If you need a painkiller it's worth considering the source of pain you are trying to kill. This is an article with a chart considering 11 different situations you might be in and which pill is better for each. A 12th line for "there is also some swelling in the part of you that hurts" would make sense to me.

I had a swelling and even mild fever from an infection and what really helped was Loxoprofen, Ibuprofen did not do anything.

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