This always blows my mind. We are currently breathing in the DNA of the trees, animals, and people around us—and we’re leaving ours behind for them, too. We’re all one big genetic soup.
At this time of year, believe me, I am aware of the inhaled tree DNA setting off my pollen allergies.
We can't make a certain HIV drug anymore because after 2 years, a lower energy crystal state formed, and that state isn't as effective. Now anytime we try to form synthesize the drug it finds a molecule of the lower energy crystal state which causes the crystal to also form in the lower energy state.
One of the important steps in mRNA vaccines was to surround the mRNA with a lipid to ensure it can survive long enough to enter a cell. Naked mRNA would not have worked.
Does it mean yes or no? I think "no", but IANAMD; IANAB, ... I think it only identify proteins, glycoproteins, and other stuff that is in the surface of the cells/virus but not the DNA/RNA.
Sure, some samples will be off to antigen presentation, but does that inform more than this is an encountered foreign substance and this is how to bind to it for neutralization ? Seems like in principle you could take the overview picture and have something like olfaction, but for things that hadn't been sufficiently cracked open when they passed the olfactory epithelium. Maybe it's starting to be sorted out, but I'm not up to date on what the neural feedback from the immune system carries.