Among those of us that have attempted or have done that port, most will probably not look particularly favorably on autotools again.
One of the easiest approaches here involves reverse-engineering the autotools product from a test run performed on a GNU/Linux box, and then translating and building a platform-specific script.
From what I can tell of it, autotools makes substantial use of GNU/Linux features. Which is certainly fine for its intended platform and typical usage, but it's an approach that is Not Fun for porting that code.