Personally I opted in to being NVIDIA-vendor-locked a couple of years ago because I just couldn't stand the insanely bonkers and pointless complexity of APIs like Vulkan. I used OpenGL before which supported all vendors, but because newer features weren't added to OpenGL I eventually had to make the switch.
I tried both Vulkan and CUDA, and after not getting shit done in Vulkan for a week I tried CUDA, and got the same stuff done in less than a day that I could not do in a whole week in Vulkan. At that moment I thought, screw it, I'm going to go NV-only now.