Thanks for bringing up Nushell.
I don't have working experience with Nushell.
Just by looking at the documentation, I think the obvious differences are:
1. Nushell is a simple shell script. Lambda is a full functional language. Nushell does not have class support.
2. Nushell does not have built-in markup data support.
3. Nushell does not have rich type, pattern matching and schema support.
4. Nushell is CLI. Lambda supports both CLI and GUI.