I mean, as someone who grew up pronouncing it "Ess-Cue-Ell", I wish I learned earlier on that "Sequel" was the intended pronunciation. :)
Even people who know because then they have to explain it which wastes time for no benefit.
But even then, it makes sense to choose to pronounce it “the wrong way”. I say “sequelite” because that’s fairly clear in context, but “sequel” might not be so I pronounce each letter in that case.
Did know PNG is supposed to be pronounced “ping”? I don’t know anyone who chooses to do that, even if they know.
(I've always pronounced PNG "ping". It's interesting that there is a split there, I'm not sure I would have expected a large one.)