If a person were looking to play a game on its release day (legitimate or pirated), they would find the process so time consuming and annoying that I doubt more than 1% of Wii owners would bother with it. I would guess the same pattern would repeat for hacked PS3s. Of course, even a 1% loss in sales would be a pretty big blow for Sony and the other developers, but it's debatable whether or not that population would have paid for a pirated game in the first place.
Does anyone know if Nintendo ever announced how much they've lost in sales to piracy on the Wii? Has Sony ever released estimates on how much they might lose to piracy?