You can use e.g. this link and then select different types of color blindness via the popover on the right:

http://colorfilter.wickline.org/?a=1;r=;l=9;j=1;u=aozora.git...

In short: Metro looks different because it uses different colors. I guess this shouldn't impact readability or accessibility in most cases due to the use of simple, sharp icons and white text. But I guess the white text could result in problems when the color blind perceive a given color as a light gray, resulting in little contrast.