Fibre and stool softeners did nothing for me. Nor increasing water. Nor exercise. Nor massaging my stomach. Nor senna

Only a magnesium drink ("Milk of Magnesia") or bisocodyl, neither of which are pleasant to take regularly as they result only in diarrhoea

It's hard to balance trying to let your body do its thing with less extreme method and resorting to the nuclear option. You also have to write off a day and not go anywhere after taking those

It's very much related to the drug and not just "ignoring" something