It's kinda a drag though because AIR actually provides a fantastic cross-platform solution for desktop apps. Even thought they are in ActionScript, it's extremely similar writing Javascript apps that have model binding.
I feel like I've tried every cross platform environment from AIR to Titanium to Java/QT to RealBasic, to Mono and none of them are quite as easy and predictable to get running as an AIR app. I guess going with straight-up C would be better but nobody on my team has that kind of experience.
Anyway, probably off topic rant, but I think AIR would be a reasonable choice for a desktop game. The main problem with it right now is that it feels like it's gone out of favor and everybody is abandoning the platform.