Why not? .NET Blazor and others already do that. In my eyes this was the whole hype of WASM. Replace JS. I don't give a crap about running node/java/whatever in the browser, why would i want that? I can run those outside the browser. I mean sure if you have some use case for it that's fine and I'm glad WASM lets you do it but I really don't see why most devs would care about that. We use the browser for browsing the web and displaying our websites.
To me the browser is for displaying websites and I make websites but I loathe JS. So being able to make websites without JS is awesome.