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I suppose that depends on the use case.

For mash-ups specifically, using yt-dlp to download music and split into stems with Demucs, using the UVR frontend, before importing into a DAW is effortless. The catch is that you can't expect to get OK-ish separation on anything other than vocals and "other", which really isn't a problem for mash-ups.

https://github.com/Anjok07/ultimatevocalremovergui

IS there any DAW plugins that do that ?

There are several. I've only tried one of them (free, can't remember which) but went back to UVR5.

While it's convenient not having to split stems into separate files beforehand, by using a VST, you usually end up doing so anyway while editing and arranging.

If you're already in the Ableton ecosystem, their newly released stem separation is actually very good, at least for the small amount of testing I've done so far. Much better than demucs, which shouldn't come as a surprise I suppose.

I use RipX DAW personally. It very cleanly seperates vocals, guitar, bass, and drums.