A thing to consider would be to make it easier (or perhaps bake it in) to separate out parts of the app into a separate origin. Something that would be good for pretty much any SaaS app would be to separate the IAM out (could still embed it with an iframe) - this allows you to keep a fairly tight security policy for the IAM stuff and a more lax one for the rest of the app. Kinda how Google separates out accounts.google.com.