being able to reply IS the ability to send to an arbitrary address, because the SMTP protocol makes it trivial to SEND an email from any arbitrary address.
The moment you allow outbound traffic, you risk being weaponized as an open relay for spam. To implement a safe 'Reply-Only' feature, Mephisto would need a sophisticated validation layer that cryptographically links the outbound reply to a specific, recently received message ID. Even then, rate-limiting would have to be extremely aggressive. For now, staying receive-only is a deliberate choice to protect the service's reputation and ensure 100% uptime.