4x founder with 2 exits. The only time conflict arose or I felt like giving up was when we weren't growing. Growth and sales can heal just about all wounds (not all, but just about all). These types of articles always seem to point out the symptoms, and not the cause.

The symptom of wanting to give up is because you aren't growing fast enough

The symptom of founder turmoil is because whatever strategy you're currently using isn't growing the company fast enough

The symptom of running out of money is because you're not hitting your sales targets