I was a laid off in the beginning of the year from my remote job, landed several interviews, and I found a new job in <2 months. My resume is less impressive than yours, ~10 years of experience.
I was able to land interviews with some remote companies. I used to work at Shopify, a got some interviews at Ruby shops from that.
Some possibilities:
1. Ageism, this is a distinct possibility.
2. You held very senior positions. I think a lot of people don't like hiring people that were more senior than them. So that CTO is being held as a negative. They are not saying "Hey I get the experience of an EM and a CTO in a Senior Engineer for a bargain salary", they are worried you will overshadow them. This is sub optimal behavior for companies.
3. Talking to people I think non-tech markets look like they are doing fine. People I know in Rochester, Syracuse, and Cleveland aren't having issues getting jobs. I think the huge layoffs in big tech have left a big supply in tech cities to less demand.