What do you talk about in two minutes? I've never had to speed-date. Ask about hobbies? Is asking about work pedestrian? Was always curious about this.
Of course, not everyone will be open to talking at any given time. And it is probably especially difficult to have a genuine connection in a speed dating context, where the other party is probably posturing in one way or another. If you met them in any other situation, they'd probably be more open/authentic.
With regular speed dating I had all sorts of chats, it usually enough for 1-3 threads of conversations.