Guardrails for anything versatile might be trivial on consideration.
As a kid I read some Asimov books where he laid out the "3 laws of robotics", first law being a robot must not harm a human. And in the same story a character gave the example of a malicious human instructing Robot A prepare a toxic solution "for science", dismissing Robot A, then having Eobot B unsuspectingly serve the "drink" to a victim. Presto, a robot killing a human. The parallel to malicious use of LLMs has been haunting me for ages.
But here's the kicker, Iirc, Asimov wasn't even really talking about robots. His point was how hard it is to align humans, for even perfectly morally upright humans to avoid being used to harm others.