I think it's pretty easy to get behind disease elimination in principle. >90% of people would be thrilled to use crispr to edit a congenital disease out of an embryo assuming it were as safe as any reasonable medical procedure can be. I think that ship is getting ready to set sail, probably not in the US at first, but the US will probably catch up eventually.

I think the more controversial conversation around human improvement needs to happen at some point as well. There's a fundamental problem with the modern world. It has changed over the last ~1000 years so much faster than our evolution could possibly keep up with, and we are now woefully unfit for it. There are so many life-threatening diseases (obesity, tribalism, depression) that are due to our behavior. To speed up and guide human evolution to make ourselves more empathetic, more reasonable, better physically suited to lifestyles revolving around thought instead of physical work, would be a huge long-term win for our species.

Of course there are inevitably a bunch of assholes trying to inject racialized agendas into this conversation, and that understandably poisons the very concept of genetic betterment for most people. But those racist tendencies are exactly the kind of outdated human nature I'm talking about eliminating.