In society, i guess, if such super-humans are designed to have a 500 year life, they have automatic adusted there pension age to something like 450 years.
In law, because such super smart super-humans allways know things better, the fines are 100 times higher.
On the other side, of course, who would not choose the best for the best for the own child. Why should a person wear glasses the whole life, if it is possible to switch a few genoms.
So many difficult questions ..