You're just being a reverse curmudgeon. Creativity thrives in an environment of diversity, and San Francisco became a mecca for creative software people because it was already a mecca for artists, hippies and people of all races and creeds, not because it was packed to the gills with iPhone developers in ironic t-shirts. Maybe there's nothing that can be done about it, but I think there's definitely a loss when a place becomes homogenous due to gentrification.
I've only been here since 2008, but even on that limited timeframe it's been pretty damned annoying to see useful places (like hardware stores, markets, dry cleaners, etc.) shut down so that room can be made for yuppie bars and overpriced restaurants. So we replace shops with co-working spaces and bookstores with boutique dealers of objets d'art and we pretend that it's "progress", but we make the neighborhoods less attractive to the people who made the neighborhoods attractive.
In short: if you're giving me a choice, I'll take "stabby" neighborhoods over luxury condos. At least the former gives an artist or a musician a place to squat while earning nothing and doing something truly novel; the latter gives a software engineer a place to live while working for Zynga.