As long as your `/usr/bin/env` supports `-S`, yes.

It will install and use distribution packages, to use PyPA's terminology; the term "module" generally refers to a component of an import package. Which is to say: the names you write here must be the names that you would use in a `uv pip install` command, not the names you `import` in the code, although they may align.

This is an ecosystem standard (https://peps.python.org/pep-0723/) and pipx (https://pipx.pypa.io) also supports it.